Our Experience of FIT Screening

Information

2022.11.01 FITCalprotectinUpdated: OC-SENSOR Ceres™
2022.11.01 FITCalprotectinEiken Chemical Launched the Fully Automated Faecal Immunochemical Test/Faecal Calprotectin Analyzer "OC-SENSOR Ceres™" [ IVDR CE Marked ]
2022.10.05 FITUpdated: Packages for Mailed FIT

Eiken Chemical launched sales of fully automated FIT analyser in 1989. Since then, we have been developing automated FIT system “OC-SENSOR” for 30 years worldwide. Approximately 100 million tests are performed per year in more than 45 countries. OC-SENSOR has been used in many academic publications and national guidelines [*3, and see publication page].

In some countries, national guidelines recommend faecal immunochemical test (FIT) as a method of population based screening for colorectal cancer [*1 European Commission, *2 UK, *3,4 US, *5 Canada]. In the recommendation statement of U.S. Preventive Service Task Force, our product OC-Sensor is mentioned as “the best test performance characteristics (ie, highest sensitivity and specificity) [*3].”

Watch the video to learn about our experiences with FIT screening.

Collection Paper

Stool sample collection paper: To take stool sample easily and adequately, placing a Collection paper can help catch stool in the toilet bowl. Eiken Chemical provides flushable paper that sampling instruction is printed.

OC-Auto Sampling Bottle 3

Stool sampling devices: OC-Auto Sampling Bottle 3 is a palm-sized stool collection device. Patients scrape the surface of stool with the probe and insert it into the bottle. After closing the device properly, the liquid does not leak out easily.

Special Envelope (left: for 1 day, right: for 2 days)

Envelope for mailing: We developed an envelope integrating absorbent pat, called Special Envelope, for OC-Auto Sampling Bottle 3. Two types of envelope are available; for 1-day and 2-day sampling method.

Data example

Eiken Quality Control Survey (EQCS):

We offer an external quality assessment service (Eiken Quality Control Survey; EQCS) for OC-SENSOR users through our local distributors. The service started in 1995 and currently more than 1500 laboratories from 20+ countries participate in the program every year. EQCS supports laboratories to assess their performance objectively by comparison of the testing results among the participants. *Currently we are conducting surveys for FIT only.

Cutoff value adjusting: Users can choose cutoff to maximize sensitivity and specificity. Studies were conducted to suggest the appropriate values in population screening [*7].

2 sized analysers: We can offer two different sized fully automated analysers OC-SENSOR PLEDIA and OC-SENSOR Ceres which can be chosen according to the scale of screening.

OC-SENSOR PLEDIA

High-end faecal test analyser for Faecal immunochemical test and Faecal calprotectin test.

Detail

OC-SENSOR Ceres

Accessible, compact, and simple to use design with comparable analytical performance to the high-end model.

Detail

Halloran S, Launoy G, Zappa M. European Commission. European guidelines for quality assurance in colorectal cancer screening and diagnosis. First edition – Faecal Occult Blood Testing. Endoscopy 2012; 44:SE65–SE87
National Institute for Health and Care Excellence. NICE guideline NG12. Suspected cancer: recognition and referral. https://www.nice.org.uk/guidance/ng12 Published 2015.
U.S. Preventive Services Task Force. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2021;325(19):1965-1977.
U.S. Multi-Society Task Force. Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer. Gastrointestinal Endoscopy, 2017; Volume 153, Issue 1, 307 - 323.
Canadian Task Force on Preventive Health Care. Recommendations on screening for colorectal cancer in primary care. CMAJ Mar 2016, 188 (5) 340-348
National Health Service. How should I collect and store a poo (stool) sample?. https://www.nhs.uk/common-health-questions/infections/how-should-i-collect-and-store-a-stool-faeces-sample/ Accessed November 2019.
van Rossum L, van Rijn A, Laheij R, et al. Cutoff value determines the performance of a semi-quantitative immunochemical faecal occult blood test in a colorectal cancer screening programme. Br J Cancer 2009;101, 1274–1281.