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Veterinary "VET-SAA Eiken"
Serum Amyloid A (SAA) assay for multispecies
VET-SAA ‘Eiken’ is a latex agglutination turbidimetric immunoassay (LTIA) for clinical chemistry analyzers.
- Species applicability: The reagent is reactive with following species: Horse, Cat, Dog, Cattle, Raccoon dog, Shetland pony, Grant's Zebra, Lion, Cheetah, Blackbuck, Water buffalo, Red Deer, Pig, Bonnet macaque, Crested macaque, Toque macaque, Patas monkey, De Brazza's guenon, Tufted capuchin, Squirrel monkey, Lar Gibbon, Ring-tailed lemur, Rabbit (In-house data)
- Analyzers applicability: VET-SAA ‘Eiken’ is designed to be used on general clinical chemistry analyzers. About applied parameters, please contact us.
SAA features
SAA is one of the major APPs that is conserved in many animal species.
Inflammation response can be clearly detected. Also, SAA concentration is considered to reflect healing condition.
Horse SAA data adopted from: Jacobsen, S., Vinther, A.M., Kjelgaard-Hansen, M. et al. Validation of an equine serum amyloid A assay with an unusually broad working range. BMC Vet Res 15, 462 (2019).
Publications of VET-SAA
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Jacobsen S, Vinther AM, Kjelgaard-Hansen M, et al. Validation of an equine serum amyloid A assay with an unusually broad working range. BMC Vet Res 15, 462 (2019). PubMed > |
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| “The assay was unique in its ability to measure SAA concentrations with acceptable reliability over an extreme concentration range. This is relevant in the equine species, where SAA concentrations may reach very high concentrations” (Jacobsen et al. 2019). |
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Lennox A, Asahi Y, Arheart K, et al. Preliminary evaluation of an immunoturbidimetric assay and lateral flow device for the measurement of serum amyloid A in rabbits. Journal of Exotic Pet Medicine. 33 (2020) 54-56. Science Direct > |
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| “Reference laboratory testing for APPs allows for accurate measurement of SAA and CRP [...] Additional studies may show that APPs can have value in the diagnosis and prognosis of diseases in rabbits.” (Lennox et al. 2020) |
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Otsuka M, Nishi Y, Tsukano K, et al. Sequential changes in hepatic mRNA abundance and serum concentration of serum amyloid A in cattle with acute inflammation caused by endotoxin. J Vet Med Sci. 82(7): 1006–1011, 2020. PubMed > |
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| “Hepatic SAA2 and SAA4 mRNA abundance significantly increased from 4 hr after administration, and remained significantly higher than those pre-values up to 12 and 24 hr, respectively. [...] The major isotype was SAA2 in liver tissue, and it is indicating systemic inflammation in cattle.” (Otsuka et al. 2020) |
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Otsuka M, Sugiyama M, Ito T, et al. Diagnostic utility of measuring serum amyloid A with a latex agglutination turbidimetric immunoassay in bovine mastitis: comparison with haptoglobin and alpha 1 acid glycoprotein. J Vet Med Sci. 83(2): 329–332, 2021. J-Stage > |
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| "Only the plasma SAA concentration in cows with clinical mastitis (44.90 mg/l; n=15) was significantly higher than that in those with subclinical mastitis (10.70 mg/l; n=16), enabling their diagnosis in contrast to other APPs. Thus, the SAA assay using a LATIA reagent is useful in assessing mastitis severity due to its higher sensitivity and specificity than other APP assays." (Otsuka et al. 2020) |
Product information
Serum amyloid A (SAA)
Veterinary Research Use Only
VET-SAA ‘Eiken’
VET-SAA ‘Eiken’ is a turbidimetric immunoassay reagent for measurement of serum amyloid A (SAA) in animal serum and plasma. The reagent is reactive with a wide range of animal SAA, such as horse, cat, dog, cattle and rabbit SAA.
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Code No. |
Product Name |
Units |
Storage (℃, degree Celsius) |
IFU |
|---|---|---|---|---|
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V-SZ51 |
VET-SAA ‘Eiken’ Reagent |
R1: 2 x 20mL R2: 2 x 20mL |
2-10℃ |
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V-SZ90 |
VET-SAA Calibrator Set |
Calibrator 5x1 mL Lysis buffer 1x12mL |
2-8℃ |
PDF file > |
|
V-SZ91 |
VET-SAA-QC-Low |
Control 5x1 mL Lysis buffer 1x12mL |
2-8℃ |
PDF file > |
|
V-SZ92 |
VET-SAA-QC-High |
Control 5x1 mL Lysis buffer 1x12mL |
2-8℃ |
PDF file > |
- *These products require keep-cool transportation and storage within the designated temperature.
- *These products are veterinary research use only. Not for human in vitro diagnostic use.