To Achieve Universal Health Coverage (UHC)

In 2015, Sustainable Development Goals (SDGs:17 Goals) are adopted at United Nations summit [*1]. In SDGs Goal 3; “Ensure healthy lives and promote well-being for all at all ages,” UHC is one of the targets to achieve.

Large global populations die of infectious diseases including tuberculosis, malaria and Neglected Tropical Diseases (NTDs), and it is mandatory to improve the healthcare immediately. However, many high burden countries don’t have access to necessary healthcare because of poverty.

To achieve UHC, Eiken Chemical contributes to realize proper and early detection of infectious diseases by providing accurate, easy and robust LAMP products. LAMP products are designed for the resource limited setting use to reach the last mile of health for the people.

 

Now it’s time to action for “No one left behind”.

LAMP technology for Continuous Threats of Infectious Diseases

Tuberculosis (TB)

TB remains one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent. Roughly 10.0 million new TB cases and 1.2 million TB-related deaths were reported in 2018 [*2].

TB LAMP is the a molecular test WHO recommends for TB diagnosis. It has been developed for use in high burden and resource limited settings.

Malaria

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. In 2018, there were approximately 228 million estimated cases and more than 400,000 deaths worldwide,  and most of countries are sub-Saharan Africa, where malaria is the leading cause of death for children under five [*3].

Malaria LAMP is a comprehensive molecular solution introduced for the diagnosis of malaria. The limit of detection is 1–2 parasites/µL, which is far lower than microscopy and RDTs. In addition, Malaria LAMP can differentiate between Plasmodium pan species.

Neglected tropical diseases (NTDs)

NTDs are a diverse group of tropical infections which are common in low-income populations in developing regions of Africa, Asia, and the Americas – They affect more than one billion people and cost developing economies billions of dollars every year [*4].

The development of the LAMP assay has provided a new tool towards the solution of the issue. LAMP does not require a thermocycler, is relatively inexpensive, and is simple to perform with high amplification sensitivity and specificity.

 

  • Leishmaniasis: Leishmaniasis, caused by protozoan parasites of the Leishmania genus, represents an important health problem in many regions of the world.
  • HAT: Human African trypanosomiasis (HAT) is a vector-borne parasitic zoonotic disease. The disease caused by Trypanosoma brucei gambiense is the most prevalent in Africa.

References

  1. United Nations “About the Sustainable Development Goals” https://www.un.org/sustainabledevelopment/sustainable-development-goals/ Accessed 9th January, 2020.
  2. WHO “Global TB Report 2019” World Health Organization, 2019: Report.
  3. World malaria report 2019. Geneva: World Health Organization; 2019. Licence: CC BY-NC-SA 3.0 IGO.
  4. Integrating neglected tropical diseases into global health and development: fourth WHO report on neglected tropical diseases. Geneva: World Health Organization; 2017. Licence: CC BY-NC-SA 3.0 IGO.

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