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Veterinary "VET-SAA Eiken"
Eiken Serum Amyloid A (SAA) Reagents
SAA assay for multispecies
VET-SAA ‘Eiken’ is a latex agglutination turbidimetric immunoassay (LTIA) for clinical chemistry analyzers.
- Species applicability: The reagent is reactive with following species: Horse, Cat, Dog, Cattle, Raccoon dog, Shetland pony, Grant's Zebra, Lion, Cheetah, Blackbuck, Water buffalo, Red Deer, Pig, Bonnet macaque, Crested macaque, Toque macaque, Patas monkey, De Brazza's guenon, Tufted capuchin, Squirrel monkey, Lar Gibbon, Ring-tailed lemur, Rabbit (In-house data)
- Analyzers applicability: VET-SAA ‘Eiken’ is designed to be used on general clinical chemistry analyzers. About application settings, please contact us.
SAA features
SAA is one of the major APPs that is conserved in many animal species.
Inflammation response can be clearly detected. Also, SAA concentration is considered to reflect healing condition.
Horse SAA data adopted from: Jacobsen, S., Vinther, A.M., Kjelgaard-Hansen, M. et al. Validation of an equine serum amyloid A assay with an unusually broad working range. BMC Vet Res 15, 462 (2019).
Publications of VET-SAA
■：Evaluated using LZ-SAA
●：Evaluated using VET-SAA
★：Evaluated using SAA-1 (prototype of VET-SAA)
Horse SAA
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| ● Jacobsen S, et al. Validation of an equine serum amyloid A assay with an unusually broad working range. BMC Vet Res. 2019;15(1):462. PubMed > | |
| ● Kiemle J, et al. Comparison of a point-of-care serum amyloid A analyzer frequently used in equine practice with 2 turbidimetric immunoassays used in human and veterinary medicine. J Vet Diagn Invest. 2022 Jan; 34(1): 42–53. PubMed> | |
| ● Jacobsen S. Use of serum amyloid A in equine medicine and surgery. Vet Clin Pathol. 2023 Feb:52 Suppl 1:8-18. PubMed> |
Cat SAA
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| ● Rossi G. Acute phase proteins in cats: Diagnostic and prognostic role, future directions, and analytical challenges. Vet Clin Pathol. 2023 Feb:52 Suppl 1:37-49. PubMed> |
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| ● Kurtz M, et al. Usefulness of serum amyloid A for the diagnosis of pyelonephritis in cats: A prospective evaluation. J Vet Intern Med. 2024 May-Jun;38(3):1542-1552. PubMed> | |
| ● Yuki M, et al. Comparison of polyclonal and monoclonal antibody assays for serum amyloid A in cats: a study based on an automated turbidimetric immunoassay in a primary care veterinary hospital. Am J Vet Res. 2024, Jul 12:1-6. PubMed> |
Dog SAA
| ● Behling-Kelly E, et al. Acute phase protein response and changes in lipoprotein particle size in dogs with systemic inflammatory response syndrome. [published online ahead of print, 2022 Apr 14]. J Vet Intern Med. 2022;10.1111/jvim.16420. PubMed > |
| ● Goggs R, et al. Serial analysis of blood biomarker concentrations in dogs with pneumonia, septic peritonitis, and pyometra. J Vet Intern Med. 2022;36(2):549-564. PubMed > |
| ★ Christensen M, et al. Canine serum amyloid A (SAA) measured by automated agglutination turbidimetry is useful for routine sensitive and specific detection of systemic inflammation in a general clinical setting. J Vet Med Sci. 2013;75:459–466. PubMed > |
| ★ Christensen M, et al. Comparison of serum amyloid A and C-reactive protein as diagnostic markers of systemic inflammation in dog. Can Vet J, 55. 2014; 161-168. PubMed > |
| ★ Viitanen SJ, et al. The utility of acute-phase proteins in the assessment of treatment response in dogs with bacterial pneumonia. J Vet Intern Med 2017;31:124–33. PubMed > |
| ★ Löfqvist K, et al. Usefulness of C-reactive protein and serum amyloid A in early detection of postoperative infectious complications to tibial plateau leveling osteotomy in dogs. Acta Vet Scand. 2018;60:30. PubMed > |
Rabbit SAA
| ● Lennox A, et al. Preliminary evaluation of an immunoturbidimetric assay and lateral flow device for the measurement of serum amyloid A in rabbits. Journal of Exotic Pet Medicine. Volume 33, April 2020, Pages 54-56 Science Direct > |
Bovine SAA
| ● Otsuka M, et al. Sequential changes in hepatic mRNA abundance and serum concentration of serum amyloid A in cattle with acute inflammation caused by endotoxin. J Vet Med Sci. 82(7): 1006–1011, 2020. PubMed > |
| ● Sasazaki N, et al. Effects of dietary feed supplementation of heat-treated Lactobacillus sakei HS-1 on the health status, blood parameters, and fecal microbial flora of Japanese Black calves. J Vet Med Sci. 2020 Oct 20;82(10):1428-1435. PubMed> |
| ● Otsuka M, et al. Diagnostic utility of measuring serum amyloid A with a latex agglutination turbidimetric immunoassay in bovine mastitis: comparison with haptoglobin and alpha 1 acid glycoprotein. J Vet Med Sci. 83(2): 329–332, 2021. J-Stage > |
| ● Okawa H, et al. Association between Anti-Müllerian Hormone Concentration and Inflammation Markers in Serum during the Peripartum Period in Dairy Cows. Animals (Basel). 2021 Apr 26;11(5):1241. PubMed> |
| ● Sasazaki N, et al. Mitigation of sterigmatocystin exposure in cattle by difructose anhydride III feed supplementation and detection of urinary sterigmatocystin and serum amyloid A concentrations. Arch Anim Breed. 2021 Jun 16;64(1):257-264. PubMed> |
| ● Widodo OS, et al. Practical Application of Urinary Zearalenone Monitoring System for Feed Hygiene Management of a Japanese Black Cattle Breeding Herd-The Relationship between Monthly Anti-Müllerian Hormone and Serum Amyloid A Concentrations. Toxins(Basel). 2022 Feb 16;14(2):143. PubMed> |
| ● Shinya U, et al. Serum Amyloid A Concentrations of Healthy and Clinically Diseased Japanese Black Breeding Cattle-Preliminary Measurements for Determining the Cut-Off Concentrations. Vet Sci. 2022 Apr 21;9(5):198. PubMed> |
| ● Widodo OS, et al. Relationship Between Ovary Size and Anti-Müllerian Hormone Levels in Holstein-Friesian Cows. Front Vet Sci. 2022 Jun 13:9:828123. PubMed> |
| ● Widodo OS, et al. Practical Application of a Urinary Zearalenone Monitoring System for Feed Hygiene Management of a Japanese Black Cattle Breeding Herd-Relevance to Anti-Müllerian Hormone and Serum Amyloid A Clarified from a Two-Year Survey. Toxins(Basel). 2023 Apr 30;15(5):317. PubMed> |
| ● Shinya U, et al. Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice. Vet Sci. 2023 Aug 17;10(8):528. PubMed> |
| ● Sasazaki N, et al. Effects of dietary feed supplementation with heat-treated Lactobacillus sakei HS-1 on the health status, blood parameters, and fecal microbes of Japanese Black calves before weaning. Vet World. 2023 Nov;16(11):2293-2302. PubMed> |
| ● Nielsen LN, et al. Performance of an automated immunoturbidimetric assay for bovine serum amyloid A. Vet Clin Pathol. 2024 Jun;53(2):229-233. PubMed> |
Product information
Serum amyloid A (SAA)
Veterinary Research Use Only
VET-SAA ‘Eiken’
VET-SAA ‘Eiken’ is a turbidimetric immunoassay reagent for measurement of serum amyloid A (SAA) in animal serum and plasma. The reagent is reactive with a wide range of animal SAA, such as horse, cat, dog, cattle and rabbit SAA.
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Code No. |
Product Name |
Units |
Storage (℃, degree Celsius) |
IFU |
|---|---|---|---|---|
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V-SZ51 |
VET-SAA ‘Eiken’ Reagent |
R1: 2 x 20mL R2: 2 x 20mL |
2-10℃ |
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V-SZ90 |
VET-SAA Calibrator Set |
Calibrator 5x1 mL Lysis buffer 1x12mL |
2-8℃ |
PDF file > |
|
V-SZ91 |
VET-SAA-QC-Low |
Control 5x1 mL Lysis buffer 1x12mL |
2-8℃ |
PDF file > |
|
V-SZ92 |
VET-SAA-QC-High |
Control 5x1 mL Lysis buffer 1x12mL |
2-8℃ |
PDF file > |
- *These products require keep-cool transportation and storage within the designated temperature.
- *These products are veterinary research use only. Not for human in vitro diagnostic use.