New papers about bovine serum amyloid A (SAA) were published. Our immunoassay reagent "VET-SAA Eiken" is used for measurement of SAA.
Otsuka M, Nishi Y, Tsukano K, et al. Sequential changes in hepatic mRNA abundance and serum concentration of serum amyloid A in cattle with acute inflammation caused by endotoxin. J Vet Med Sci. 82(7): 1006–1011, 2020. PubMed >
|“Hepatic SAA2 and SAA4 mRNA abundance significantly increased from 4 hr after administration, and remained significantly higher than those pre-values up to 12 and 24 hr, respectively. [...] The major isotype was SAA2 in liver tissue, and it is indicating systemic inflammation in cattle.” (Otsuka et al. 2020)|
Otsuka M, Sugiyama M, Ito T, et al. Diagnostic utility of measuring serum amyloid A with a latex agglutination turbidimetric immunoassay in bovine mastitis: comparison with haptoglobin and alpha 1 acid glycoprotein. J Vet Med Sci. ADVANCE ONLINE PUBLICATION. doi: 10.1292/jvms.20-0550 J-Stage >
|"Only the plasma SAA concentration in cows with clinical mastitis (44.90 mg/l; n=15) was significantly higher than that in those with subclinical mastitis (10.70 mg/l; n=16), enabling their diagnosis in contrast to other APPs. Thus, the SAA assay using a LATIA reagent is useful in assessing mastitis severity due to its higher sensitivity and specificity than other APP assays." (Otsuka et al. 2020)|